The following clinically significant adverse reactions are described elsewhere in the labeling:
The following adverse reactions in Table 5 have been reported in clinical studies or postmarketing reports in patients receiving intravenously administered potassium phosphates. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
System Organ Class | Adverse Reactions |
Metabolism and Nutrition Disorders | pulmonary embolism due to pulmonary vascular precipitates [see Warnings and Precautions (5.2)], hyperkalemia [see Warnings and Precautions (5.3)], hyperphosphatemia [see Warnings and Precautions (5.4)], hypocalcemia [see Warnings and Precautions (5.5)], hypovolemia, and osmotic diuresis |
Cardiac Disorders | hypotension, arrhythmia, heart block, cardiac arrest, bradycardia, chest pain, ECG changes [see Warnings and Precautions (5.1)], and edema |
Respiratory, Thoracic, and Mediastinal Disorders | dyspnea [see Warnings and Precautions (5.2)] |
Renal and Urinary Disorders | acute phosphate nephropathy (i.e., nephrocalcinosis with acute kidney injury), decreased urine output, and transition to chronic kidney disease [see Warnings and Precautions (5.4)] |
Gastrointestinal Disorders | diarrhea, stomach pain |
Musculoskeletal and Connective Tissue Disorders | weakness |
Nervous System Disorders | confusion, lethargy, paralysis, paresthesia |
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