(dofetilide)

Medication Guide

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Health Professional Information

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Prescribing Information

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Health Professional Information

Who should not take TIKOSYN?

Who should not take TIKOSYN?

Do not take TIKOSYN if you:

•
have an irregular heartbeat called long QT syndrome
•
have kidney problems or are on kidney dialysis
•
take any of these medicines:
•
cimetidine (TAGAMET, TAGAMET HB)1
•
verapamil (CALAN, CALAN SR, COVERA-HS, ISOPTIN, ISOPTIN SR, VERELAN, VERELAN PM, TARKA)1
•
ketoconazole (NIZORAL, XOLEGEL, EXTINA)1
•
trimethoprim alone (PROLOPRIM, TRIMPEX)1 or the combination of trimethoprim and sulfamethoxazole (BACTRIM, SEPTRA SULFATRIM)1
•
prochlorperazine (COMPAZINE, COMPO)1
•
megestrol (MEGACE)1
•
dolutegravir (TIVICAY)1
•
hydrochlorothiazide alone or in combination with other medicines (such as ESIDRIX, EZIDE, HYDRODIURIL, HYDRO-PAR, MICROZIDE, or ORETIC)1
 
Ask your doctor if you are not sure if any of your medicines are the kind listed above.
•
are allergic to dofetilide in TIKOSYN. See the end of this leaflet for a complete list of ingredients in TIKOSYN.

Additional Resources

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Pfizer Safety Reporting Site

*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.

If you cannot use the above website to report an adverse event related to a Pfizer medication, please call (800) 438-1985.

You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatch or by calling (800) 332-1088.