(conjugated estrogens)
Medication Guide
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Prescribing Information
Highlights
HIGHLIGHTS OF PRESCRIBING INFORMATIONThese highlights do not include all the information needed to use PREMARIN safely and effectively. See full prescribing information for PREMARIN. PREMARIN® (conjugated estrogens) tablets, for oral use Initial U.S. Approval: 1942 WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER and PROBABLE DEMENTIASee full prescribing information for complete boxed warning.Estrogen-Alone Therapy
Estrogen Plus Progestin Therapy
INDICATIONS AND USAGEPREMARIN is a mixture of estrogens indicated for:
DOSAGE AND ADMINISTRATIONDOSAGE FORMS AND STRENGTHSTablets: 0.3, 0.45, 0.625, 0.9, and 1.25 mg (3) CONTRAINDICATIONS
WARNINGS AND PRECAUTIONSADVERSE REACTIONSMost common adverse reactions (≥5%) are: abdominal pain, asthenia, pain, back pain, headache, flatulence, nausea, depression, insomnia, breast pain, endometrial hyperplasia, leucorrhea, vaginal hemorrhage, and vaginitis. (6.1) DRUG INTERACTIONS
USE IN SPECIFIC POPULATIONS
See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling. Revised: 4/2025 |
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