(nirmatrelvir tablets; ritonavir tablets)

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How should I take PAXLOVID?

How should I take PAXLOVID?

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Take PAXLOVID exactly as your healthcare provider tells you to take it.
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PAXLOVID consists of 2 medicines: nirmatrelvir tablets and ritonavir tablets. The 2 medicines are taken together for 5 days.
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Nirmatrelvir is an oval, pink tablet.
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Ritonavir is a white or off-white tablet.
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PAXLOVID is available in 3 Dose Packs (see Figures A, B, and C below). Your healthcare provider will prescribe the PAXLOVID Dose Pack that is right for you. Follow the instruction for the Dose Pack you receive.
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If you have kidney disease, your healthcare provider may prescribe a lower dose (see Figures B and C). Talk to your healthcare provider to make sure you receive the correct Dose Pack.

Figure A

If you are prescribed PAXLOVID 300 mg; 100 mg Dose Pack
Each dose contains 3 tablets taken together twice daily

Figure A

How to take PAXLOVID 300 mg; 100 mg Dose Pack

Figure A1

Morning Dose:
Take the 2 pink nirmatrelvir tablets and
1 white to off-white ritonavir tablet together.

Figure A2 Figure A3

Bedtime Dose:
Take the 2 pink nirmatrelvir tablets and
1 white to off-white ritonavir tablet together.

Figure A4

Figure B

If you are prescribed PAXLOVID 150 mg; 100 mg Dose Pack
Each dose contains 2 tablets taken together twice daily

Figure B

How to take PAXLOVID 150 mg; 100 mg Dose Pack

Figure B1

Morning Dose:
Take the 1 pink nirmatrelvir tablet and
1 white ritonavir tablet together.

Figure B2 Figure B3

Bedtime Dose:
Take the 1 pink nirmatrelvir tablet and
1 white ritonavir tablet together.

Figure B4

Figure C

If you are prescribed PAXLOVID 300 mg; 100 mg (Day 1) and 150 mg; 100 mg (Days 2-5)
Each dose is taken together once daily; on days of dialysis take PAXLOVID after receiving dialysis

Figure C

How to take PAXLOVID 300 mg; 100 mg (Day 1) and 150 mg; 100 mg (Days 2-5)

Figure C1

Day 1 (First Day):

Take the 2 pink nirmatrelvir tablets and
1 white ritonavir tablet together
(Blue part of the blister card).

Figure C2

Days 2-5:

Take the 1 pink nirmatrelvir tablet and

1 white ritonavir tablet together

(Pink part of the blister card).

Figure C3

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Do not remove your PAXLOVID tablets from the blister card before you are ready to take your dose.
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If you are taking PAXLOVID tablets twice daily (Figure A or Figure B), take your first dose of PAXLOVID in the morning or at bedtime, depending on when you pick up your prescription, or as your healthcare provider tells you to. Take your doses at around the same time each day.
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If you have severe kidney disease and are taking PAXLOVID tablets once daily (Figure C), follow the daily dose instruction on the blister card. Take your dose at around the same time each day.
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Swallow the tablets whole. Do not chew, break, or crush the tablets.
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Take PAXLOVID with or without food.
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Do not stop taking PAXLOVID without talking to your healthcare provider, even if you feel better.
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If you miss a dose of PAXLOVID within 8 hours of the time it is usually taken, take it as soon as you remember. If you miss a dose by more than 8 hours, skip the missed dose and take the next dose at your regular time. Do not take 2 doses of PAXLOVID at the same time.
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If you take too much PAXLOVID, call your healthcare provider or go to the nearest hospital emergency room right away.
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If you are taking a ritonavir- or cobicistat-containing medicine to treat hepatitis C or HIV-1 infection, you should continue to take your medicine as prescribed by your healthcare provider.

Talk to your healthcare provider if you do not feel better or if you feel worse after 5 days.

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