(marstacimab-hncq)

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Prescribing Information

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How should I use HYMPAVZI?

How should I use HYMPAVZI?

See the detailed “Instructions for Use” that comes with your HYMPAVZI for information on how to inject a dose of HYMPAVZI, and how to properly throw away (dispose of) used HYMPAVZI prefilled syringe or HYMPAVZI prefilled pen.

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Use HYMPAVZI exactly as prescribed by your healthcare provider.
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Your healthcare provider will provide instructions for stopping (discontinuing) your current treatment when switching from factor- or non-factor-based medicines to HYMPAVZI.
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HYMPAVZI is given as an injection under your skin (subcutaneous injection) by you or your caregiver.
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Your healthcare provider should show you or your caregiver how to inject HYMPAVZI before you inject yourself for the first time.
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Do not attempt to inject yourself or another person unless you have been taught how to do so by a healthcare provider.
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Your first dose (loading dose) of HYMPAVZI is 300 mg (two 150 mg injections). Then you will inject a weekly (maintenance) dose as prescribed by your healthcare provider.
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Inject HYMPAVZI 1 time a week on the same day each week. Inject HYMPAVZI at any time of day.
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Your healthcare provider will provide information on the treatment of breakthrough bleeding during your treatment with HYMPAVZI. Do not use HYMPAVZI to treat breakthrough bleeding.
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If you miss a maintenance dose of 150 mg of HYMPAVZI:
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Give the dose as soon as possible before the next scheduled dose, and then continue with your usual 150 mg weekly dosing schedule. You may inject your next dose at your regularly scheduled time or continue dosing based on the new day you injected your missed dose. In case you are not sure when to inject HYMPAVZI, call your healthcare provider.
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If more than 13 days have passed since your last dose was given, call your healthcare provider right away for dosing instructions.
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If you miss 1 or more doses of maintenance dose of 300 mg of HYMPAVZI:
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Give a dose as soon as possible, and then continue with your 300 mg weekly dosing schedule. You may inject your next dose at your regularly scheduled time or continue dosing based on the new day you injected your missed dose. In case you are not sure when to inject HYMPAVZI, call your healthcare provider.

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