(estradiol)

Medication Guide

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Prescribing Information

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Who should not use ESTRING?

Who should not use ESTRING?

Do not start using ESTRING if you:

•
have unusual vaginal bleeding
 
Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
•
currently have or have had certain cancers
 
Estrogens may increase the chance of getting certain types of cancers, including cancer of the breast or uterus. If you have or had cancer, talk with your healthcare provider about whether you should use ESTRING.
•
had a stroke or heart attack
•
currently have or have had blood clots
•
currently have or have had liver problems
•
have been diagnosed with a bleeding disorder
•
are allergic to ESTRING or any of its ingredients
 
See the list of ingredients in ESTRING at the end of this leaflet.
•
think you may be pregnant
 
ESTRING is not for pregnant women. If you think you may be pregnant, you should have a pregnancy test and know the results. Do not use ESTRING if the test is positive and talk to your healthcare provider.

Additional Resources

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To report an adverse event related to a Pfizer product and you are not part of a clinical trial* for this medication, click the link below to submit your information: 
Pfizer Safety Reporting Site

*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.

If you cannot use the above website to report an adverse event related to a Pfizer medication, please call (800) 438-1985.

You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatch or by calling (800) 332-1088.