(estradiol)

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Prescribing Information

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What is the most important information I should know about ESTRING (an estrogen hormone)?

What is the most important information I should know about ESTRING (an estrogen hormone)?

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Using estrogen-alone may increase your chance of getting cancer of the uterus (womb).
 
Report any unusual vaginal bleeding right away while you are using ESTRING. Vaginal bleeding after menopause may be a warning sign of cancer of the uterine (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
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Do not use estrogen-alone to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).
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Using estrogen-alone may increase your chances of getting strokes or blood clots.
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Using estrogen-alone may increase your chance of getting dementia, based on a study of women 65 years of age or older.
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Do not use estrogens with progestins to prevent heart disease, heart attacks, strokes, or dementia.
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Using estrogens with progestins may increase your chance of getting heart attacks, strokes, breast cancer, or blood clots.
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Using estrogens with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.
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You and your healthcare provider should talk regularly about whether you still need treatment with ESTRING.

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