What are the possible side effects of Docetaxel Injection?

•

See "What is the most important information I should know about Docetaxel Injection?"

•

Neurologic problems. Neurologic symptoms are common in people who receive Docetaxel Injection but can be severe. Tell your healthcare provider right away if you have numbness, tingling, or burning in your hands or feet (peripheral neuropathy) or weakness of your legs, feet, arms, or hands (motor weakness).

•

Vision problems including blurred vision or loss of vision. Tell your healthcare provider right away if you have any vision changes.

•

Docetaxel Injection contains alcohol. The alcohol content in Docetaxel Injection may impair your ability to drive or use machinery right after receiving Docetaxel Injection. Consider whether you should drive, operate machinery or do other dangerous activities right after you receive Docetaxel Injection treatment.

•

Tumor lysis syndrome (TLS). TLS is caused by the fast breakdown of cancer cells. TLS can cause kidney failure, the need for dialysis treatment, or heart problems, and may lead to death. Your healthcare provider will do blood tests to check for TLS when you first start treatment and during treatment with Docetaxel Injection. Tell your healthcare provider right away if you have any symptoms of TLS during treatment with Docetaxel Injection, including:

o

nausea

o

vomiting

o

confusion

o

shortness of breath

o

irregular heartbeat

o

dark or cloudy urine

o

reduced amount of urine

o

unusual tiredness

o

muscle cramps

•

You may experience side effects of Docetaxel Injection that may impair your ability to drive, use tools, or operate machines. If this happens, do not drive or use any tools or machines before discussing with your healthcare provider.

The most common side effects of Docetaxel Injection include:

•

infections

•

low white blood cells (help fight infections), low red blood cells (anemia), and low platelets (help blood to clot)

•

allergic reactions (See "What is the most important information I should know about Docetaxel Injection?")

•

changes in your sense of taste

•

shortness of breath

•

constipation

•

decreased appetite

•

changes in your fingernails or toenails

•

swelling of your hands, face, or feet

•

feeling weak or tired

•

joint and muscle pain

•

nausea and vomiting

•

diarrhea

•

mouth or lip sores

•

hair loss: in some people, permanent hair loss has been reported

•

redness of the eye, excess tearing

•

skin reactions at the site of Docetaxel Injection administration such as increased skin pigmentation, redness, tenderness, swelling, warmth or dryness of the skin

•

tissue damage if Docetaxel Injection leaks out of the vein into the tissues

Tell your healthcare provider if you have a fast or irregular heartbeat, severe shortness of breath, dizziness or fainting during your infusion. If any of these events occurs after your infusion, get medical help right away.
Docetaxel Injection may affect fertility in males. Talk to your healthcare provider if this is a concern for you.
These are not all of the possible side effects of Docetaxel Injection. For more information, ask your healthcare provider or pharmacist.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.