(glasdegib)

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What are the possible side effects of DAURISMO?

What are the possible side effects of DAURISMO?

DAURISMO can cause serious side effects, including:
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See "What is the most important information I should know about DAURISMO?"
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Changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life-threatening. Tell your healthcare provider right away if you feel faint, lightheaded, dizzy, or feel your heart beating irregularly or fast during treatment with DAURISMO.
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Muscle Problems. Muscle problems are common with DAURISMO, but can also sometimes be serious. DAURISMO can increase your risk of muscle pain or muscle spasms. Tell your healthcare provider right away if you develop any new or worsening muscle spasms, pain, tenderness or weakness during and after treatment with DAURISMO. Your healthcare provider should do a blood test to check for muscle problems and to check your kidney function before you start taking DAURISMO, during treatment, and if you develop muscle problems.

The most common side effects of DAURISMO with cytarabine include:

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low red blood cell count (anemia)
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tiredness
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bleeding
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fever with low white blood cell count
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muscle pain
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swelling of arms or legs
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low platelet count
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nausea
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shortness of breath
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decreased appetite
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changes in taste
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pain or sores in your mouth or throat
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constipation
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rash

DAURISMO may affect fertility in males. Talk to your healthcare provider if this is a concern for you.
These are not all of the possible side effects of DAURISMO.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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