(bosutinib)

Medication Guide

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Prescribing Information

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How should I take BOSULIF?

How should I take BOSULIF?

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Take BOSULIF exactly as prescribed by your doctor.
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Do not change your dose or stop taking BOSULIF without first talking with your doctor.
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If your child takes BOSULIF, your healthcare provider will change the dose as your child grows.
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Take BOSULIF with food.
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Swallow BOSULIF tablets whole. Do not crush, break, chew or cut BOSULIF tablets. Do not touch or handle crushed or broken BOSULIF tablets.
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Swallow BOSULIF capsules whole. If you cannot swallow BOSULIF capsules whole, tell your healthcare provider.
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If you cannot swallow BOSULIF capsules whole, see the “Instructions for Use” for detailed instructions on how to prepare and give a dose of BOSULIF capsules by opening the capsules and mixing the capsule contents with applesauce or yogurt.
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If you take an antacid or H2 blocker medicine, take it at least 2 hours before or 2 hours after BOSULIF. If you take a Proton Pump Inhibitor (PPI) medicine, talk to your doctor or pharmacist.
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You should avoid grapefruit, grapefruit juice, and supplements that contain grapefruit extract during treatment with BOSULIF. Grapefruit products increase the amount of BOSULIF in your body.
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If you miss a dose of BOSULIF, take it as soon as you remember. If you miss a dose by more than 12 hours, skip that dose and take your next dose at your regular time. Do not take 2 doses at the same time.
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If you take too much BOSULIF, call your doctor or go to the nearest hospital emergency room right away.

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