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Dosage and Administration

2 DOSAGE AND ADMINISTRATION

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Initiate treatment in a coronary care or similar unit immediately after the patient's hemodynamic condition has stabilized.

Begin treatment in this early phase with the intravenous administration of three bolus injections of 5 mg of Metoprolol tartrate each; give the injections at approximately 2-minute intervals. During the intravenous administration of Metoprolol tartrate, monitor blood pressure, heart rate, and electrocardiogram.

Transition to Oral Metoprolol:

Following administration of Metoprolol tartrate Injection, transition patients to an oral formulation of metoprolol. See prescribing information for oral metoprolol for dose selection.

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