What is INLYTA?

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in combination with avelumab or pembrolizumab as your first treatment.

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alone when 1 prior drug treatment regimen for your RCC has not worked.

It is not known if INLYTA is safe and effective in children.

Before taking INLYTA, tell your healthcare provider about all of your medical conditions, including if you:

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have high blood pressure

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have thyroid problems

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have liver problems

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have a history of blood clots in your veins or arteries (types of blood vessels), including stroke, heart attack, or change in vision

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have any bleeding problems

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have a history of heart problems, including heart failure

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have an unhealed wound

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plan to have surgery or have had a recent surgery. You should stop taking INLYTA for at least 2 days before planned surgery. See "What are the possible side effects of INLYTA?"

For females, tell your healthcare provider if you:

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are pregnant or plan to become pregnant. Taking INLYTA during pregnancy can harm your unborn baby. You should not become pregnant during treatment with INLYTA.

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are able to become pregnant. You should have a pregnancy test before you start treatment with INLYTA. Use effective birth control during treatment and for 1 week after your last dose of INLYTA. Talk to your healthcare provider about birth control methods that you can use to prevent pregnancy during this time.

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are breastfeeding or plan to breastfeed. It is not known if INLYTA passes into your breast milk. Do not breastfeed during treatment and for 2 weeks after your last dose of INLYTA.

For males with female partners who are able to become pregnant:

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Use effective birth control during treatment and for 1 week after your last dose of INLYTA.

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If your female partner becomes pregnant during your treatment with INLYTA, tell your healthcare provider right away.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. INLYTA and certain other medicines can affect each other causing serious side effects.
Talk with your healthcare provider before you start taking any new medicine. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.