(clindamycin)
Clindamycin phosphate is a water-soluble ester of the semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The monohydrate form has a molecular weight of 522.98, and the molecular formula is C18H34ClN2O8PS•H2O. The structural formula is represented below:
CLEOCIN Vaginal Ovules are semisolid, white to off-white suppositories for intravaginal administration. Each 2.5 g suppository contains clindamycin phosphate equivalent to 100 mg clindamycin in a base consisting of a mixture of glycerides of saturated fatty acids.
DIRECTIONS FOR USE
How do I use CLEOCIN Vaginal Ovules?
For vaginal use only. Do not take by mouth.
Use one CLEOCIN Vaginal Ovule daily, preferably at bedtime, for 3 days in a row.
Do not use this product if the foiled pouches containing vaginal ovules are torn, opened, or incompletely sealed.
Read the full directions below before using.
Insertion without the applicator:
Figure 2
Figure 3
STORAGE CONDITIONS:
Store at 25°C (77°F); excursions permitted to 15 – 30°C (59 – 86°F) [see USP Controlled Room Temperature].
Caution: Avoid heat over 30°C (86°F). Avoid high humidity. See end of carton for the lot number and expiration date.
LAB-0649-4.0
Revised February 2026
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