(clindamycin)
DESCRIPTION
DESCRIPTION
Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α–D-galacto-octopyranoside 2-(dihydrogen phosphate). It has a molecular weight of 504.96, and the molecular formula is C18H34ClN2O8PS. The structural formula is represented below:
CLEOCIN Vaginal Cream 2%, is a semi-solid, white cream, which contains 2% clindamycin phosphate, USP, at a concentration equivalent to 20 mg clindamycin per gram. The pH of the cream is between 3.0 and 6.0. The cream also contains benzyl alcohol, cetostearyl alcohol, mixed fatty acid esters, mineral oil, polysorbate 60, propylene glycol, purified water, sorbitan monostearate, and stearic acid.
Each applicatorful of 5 grams of vaginal cream contains approximately 100 mg of clindamycin phosphate.
DIRECTIONS FOR USE
DIRECTIONS FOR USE
Disposable plastic applicators are provided with this package. They are designed to allow proper vaginal administration of the cream.
Remove cap from cream tube. Screw a plastic applicator on the threaded end of the tube.
Rolling tube from the bottom, squeeze gently and force the medication into the applicator. The applicator is filled when the plunger reaches its predetermined stopping point.
Unscrew the applicator from the tube and replace the cap.
While lying on your back, firmly grasp the applicator barrel and insert into vagina as far as possible without causing discomfort.
Slowly push the plunger until it stops.
Carefully withdraw applicator from vagina, and discard applicator.
REMEMBER TO APPLY ONE APPLICATORFUL EACH NIGHT BEFORE BEDTIME, OR AS PRESCRIBED BY YOUR DOCTOR.
INSTRUCCIONES PARA LA PACIENTE
Este envase contiene aplicadores de plástico desechables. Los aplicadores están diseñados para la administración apropiada de la crema en la vagina.
Remueva la tapa del tubo de crema y enrosque el aplicador de plástico al tubo.
Exprima el tubo suavemente desde el extremo inferior y fuerce el medicamento al aplicador. El aplicador estará lleno cuando el émbolo llega a su máxima longitud.
Desenrosque el aplicador del tubo y vuelva a poner la tapa.
Acuéstese de espalda y agarrando firmemente el aplicador, introdúzcalo en la vagina tanto como sea posible sin causar molestias.
Empuje lentamente el émbolo hasta que se detenga.
Saque el aplicador cuidadosamente de la vagina y descártelo.
RECUERDE APLICARSE UN APLICADOR LLENO TODAS LAS NOCHES AL ACOSTARSE, O DE ACUERDO CON LAS INDICACIONES DE SU MEDICO.
LAB-1058-1.0
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